Meconio: vehiculo de biomarcadores de exposición a sustancias psicoactivas en gestantes

Meconio: vehiculo de biomarcadores de exposición a sustancias psicoactivas en gestantes

Children exposed to drugs in a prenatal way are a medical and social problem. A useful way to study this problemis by analyzing biological matrices, such as the meconium, which stores psychoactive substances or their metabolites.To determine its fetal exposure the most common system is the analysis of blood from the umbilical cord, urine fromthe mother, or urine from the new born. Meconium is inert and it is easily obtainable. It stores psychoactive substancesor its metabolites from week 12 of gestation and they are fossilized in it until birth. It can be a very important instrumentto investigate fetal exposure to several drugs of abuse. It is necessary to know the degree of fetal exposure tocontribute to the prognosis and timely pathology treatment which, due to the lack of clinical relevant manifestations,can be overlooked and require the implementation of tests that use reliable biological matrices.

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23. DOI: http://dx.doi.org/10.22490/24629448.377