Absence of interferences for heterophilic antibodies in the quantification de cardiacTroponin I, in patients with terminal chronic renal inadequacy in hemodialysis treatment

Ausencia de interferencias por anticuerpos heterófilos en la cuantificación de Troponina I Cardíaca, en pacientes con insuficiencia renal crónica terminal en tratamiento de hemodiálisis

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Absence of interferences for heterophilic antibodies in the quantification de cardiacTroponin I, in patients with terminal chronic renal inadequacy in hemodialysis treatment. (2014). NOVA, 1(1). https://doi.org/10.22490/24629448.1048
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Carmen Cecilia Almonacid
Universidad Colegio Mayor de Cundinamarca. Bogotá, Colombia.
    Jorge Cantillo Turbay
    Servicio de Terapia Renal Hospital Universitario Clínica San Rafael. Bogotá, Colombia.
      Janneth Carolina Quintana
      Universidad Colegio Mayor de Cundinamarca. Bogotá, Colombia.
        Lorena Astrid Quiroga
        Universidad Colegio Mayor de Cundinamarca. Bogotá, Colombia.
          Yolima Andrea Parrado
          Universidad Colegio Mayor de Cundinamarca. Bogotá, Colombia.
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            The present study seeks to value the behavior of the addition of the blocking reagent of heterophilic antibodies (HBR), in the cardiac Troponin I quantification in patient with terminal chronicle renal inadequacy subjected to hemodialysis treatment. To each one of 70 patients with IRCt in hemodialysis treatment in the San Rafael University Hospital of Bogot·, they were taken a sample of serum and one of plasm heparanized in the pre dialysis, in which the TnIc concentrations were quantified with and without HBR addition, by means of the enzimoinmunoassay Axsym. The statistical test of Wilcoxon was used. The TnIc values in plasms and serums with and without the HBR addition didn't show significant differences (0.113 and 0.666 respectively), so much in the total of the patients as in those with chronic cardiac illness. Not having found differences in the TnIc values with and without HBR it takes us to think of the absence of heterophilic antibodies or in that the blocking reagent HBR doesn't have action in this population of patients.

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            20. DOI: http://dx.doi.org/10.22490/24629448.1048
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