Correlation between insulin resistance and T3 in adolescents with risk factors for developing diabetes

Correlación entre la resistencia a la insulina y T3 en adolescentes con factores de riesgo para el desarrollo de diabetes

Published 2015-06-30

Open | Download
PDF (Spanish) FLIP HTML (Spanish)
Issue
Vol. 13 No. 23 (2015)
Section
Artículo Original Producto de Investigación
How to Cite
Camarillo Romero, S., Camarillo-Romero, E., Medieta-Zeron, H., Garduño-García, J. de J., & Huitrón-Bravo, G. (2015). Correlation between insulin resistance and T3 in adolescents with risk factors for developing diabetes. NOVA, 13(23). https://doi.org/10.22490/24629448.1700
DOI

https://doi.org/10.22490/24629448.1700
Dimensions
PlumX
license

Licencia Creative Commons

NOVA by http://www.unicolmayor.edu.co/publicaciones/index.php/nova is distributed under a license creative commons non comertial-atribution-withoutderive 4.0 international.

Furthermore, the authors keep their property intellectual rights over the articles.

 

Socorro Camarillo Romero
Universidad Autónoma del Estado de México
    Eneida Camarillo-Romero
    Universidad Autónoma del Estado de México
      Hugo Medieta-Zeron
      Universidad Autónoma del Estado de México
        José de Jesús Garduño-García
        Universidad Autónoma del Estado de México
          Gerardo Huitrón-Bravo
          Universidad Autónoma del Estado de México
            Show authors biography
            Objective: To stablish the correlation between serum triiodothyronine concentrations and insulin resistance by HOMA index in a group of adolescent men with risk factors for developing diabetes. Material and Methods. It ́s a descriptive cross-sectional study. The paricipants were adolescents with some risk factor for diabetes. The presence of metabolic syndrome using the modified ATPIII criteria modified by Cook. T3, T4, TSH and basal insulin were determined in all subjets. HOMA index was calculated for insulin resistance. Results. 36 men with an average age of 15.97 ± 0.9 years were studied. There was positive correlation between T3 and HOMA-IR (r = 0.380 p = 0.022), in the full population, when analyzing only the group of metabolic syndrome, the correlation increased (r = 0.647 p = 0.031). We confirm the existence of a positive correlation between the HOMA index and the T3 concentration.

            Article visits 172 | PDF visits 113

            Downloads

            Download data is not yet available.
            1. ENSANUT 2012. Encuesta nacional de salud y nutricion. 2012. INSP. México.
            2. Raman K. Marwaha, Nikhil Tandon, M. K. Garg, Mohd Ashraf Ganie, A. Narang, Neena Mehan, Kuntal. Impact of Body Mass Index on Thyroid Functions in Indian Children. Clin Endocrinol. 2013;79(3):424-428.
            3. Tarcin O, Abanonu GB, Yazici D, Tarcin O. Association of metabolic syndrome parameters with TT3 and FT3/FT4 ratio in obese Turkish population. Metab Syndr Relat Disord. 2012 Apr;10(2):137-42. doi: 10.1089/met.2011.0098. Epub 2012 Jan 9.
            4. Rezzonico J, Niepomniszcze H, Rezzonico M, Pusiol E, Alberto M, Brenta G.Thyroid. The association of insulin resistance with subclinical thyrotoxicosis. 2011 Sep;21(9):945-9. doi: 10.1089/thy.2010.0402. Epub 2011 Aug 11.
            5. Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WH. Prevalence of a metabolic syndrome phenotype in adolescents: findings from the third National Health and Nutrition Examination Survey, 1988-1994. Archives of pediatrics & adolescent medicine. 2003;157(8):821-7. Epub 2003/08/13Dessein PH, Joffe BI, Stanwix AE. Subclinical hypothyroidism is associated with insulin resistance in rheumatoid arthritis. Thyroid. 2004 Jun;14(6):443-6.
            6. American Diabetes Association. Type 2 diabetes in children and adolescents. Diabetes Care. 2000;23(3):381–389.
            7. Camarillo-Romero Eneida, Domínguez García Ma Victoria, Amaya-Chávez Araceli, Huitrón-Bravo Gerardo, Majluf-Cruz Abraham. Dificultades en la clasificación del síndrome metabólico: El ejemplo de los adolescentes en México. Salud Pub Méx. 2010; 52(6): 524-527.
            8. Halley-Castillo E, Borges G, Talavera JO, Orozco R, Vargas-Alemán C, Huitrón Bravo G, et al. Body mass index and the prevalence of metabolic syndrome among children and adolescents in two Mexican populations. J Adolesc Health 2007;40(6):521-526
            9. Keskin M, Kurtoglu S, Kendirci M, Atabek ME, Yazici C. Homeostasis Model Assessment Is More Reliable Than the Fasting Glucose/Insulin Ratio and Quantitative Insulin Sensitivity Check Index for Assessing Insulin Resistance Among Obese Children and Adolescents. Peditrics. 2005; 115(4): 500-503.
            10. Xu M, Bi Y, Cui B, Hong J, Wang W, Ning G. The new perspectives on genetic studies of type 2 diabetes and thyroid diseases. Curr Genomics. 2013 Mar;14(1):33-48.
            11. Dessein PH, Joffe BI and Stanwix AE. Subclinical Hypothyroidism is Associated with Insulin Resistance in Rheumatoid Arthritis. Thyroid. 2004, 14(6): 443-446.
            12. Ferré N, Feliu A, García-Heredia A, Marsillach J, París N, Zaragoza-Jordana M, Mackness B, Mackness M, Escribano J, Closa-Monasterolo R, Joven J, Camps J. Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome. Clin Biochem. 2013 Sep 10.
            13. Vatner DF, Weismann D, Beddow SA, Kumashiro N, Erion DM, Liao XH, Grover GJ, Webb P, Phillips KJ, Weiss RE, Bogan JS, Baxter J, Shulman GI, Samuel VT. Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E89-100
            14. Canani LH, Capp C, Dora JM, Meyer EL, Wagner MS, Harney JW, Larsen PR, Gross JL, Bianco AC, Maia AL. The Type 2 Deiodinase A/G (Thr92Ala) Polymorphism Is Associated with Decreased Enzyme Velocity and Increased Insulin Resistance in Patients with Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2005 Jun;90(6):3472-3478.
            15. ==========================================
            16. DOI: http://dx.doi.org/10.22490/24629448.1700
            Tutorials

            Autors:

            How send article?

            Evaluator pair

            How to evaluate an article?

            Information

            Keywords

            Google Scholar profile

            Is part of
             
            Más leídos en los últimos 30 días

            Current Issue

            Sistema OJS 3.4.0.5 - Metabiblioteca |