Hematological and non-hematological diseases related to the ABO phenotype
Enfermedades hematológicas y no hematológicas relacionadas con el fenotipo ABO en pacientes de una unidad hospitalaria de Medellín.
NOVA by http://www.unicolmayor.edu.co/publicaciones/index.php/nova is distributed under a license creative commons non comertial-atribution-withoutderive 4.0 international.
Furthermore, the authors keep their property intellectual rights over the articles.
Perfil Google Scholar
Show authors biography
Introduction: The ABO blood system is composed of A and B antigens, which vary according to nucleotide substitutions, which determine the specificity of the enzyme for which they code. Its clinical importance extends beyond transfusion processes, apparently it is involved in the pathophysiology of various diseases, such as cancer, infections, cardiovascular disorders, among others. Methodology: retrospective descriptive study, with 2708 ABO blood group classification data in hospitalized patients. The Chi2 test of independence was performed to determine the relationship between hematological and non-hematological diseases and blood group. Results: Blood group O was present in 59.2% and AB in 18% of the patients; the clinical entities that predominated were non-hematological ones; Among them the most frequent were gastrointestinal bleeding, diabetes mellitus and fractures for both group A and B. In group AB, tuberculosis and gastrointestinal bleeding occurred. For diseases of the blood and hematopoietic organs, anemia of unspecified type predominated in blood groups A, AB and O, while in group B there was sickle cell anemia in crisis. Conclusion: in the present study, the relationship between blood group antigens and the development of a particular clinical entity could not be established from the statistical analysis, but from the clinical point of view, the trend of a higher frequency could be observed. of a disease in a specific blood group.
Article visits 332 | PDF visits 260
Downloads
REFERENCIAS BIBLIOGRÁFICAS
1. González-Ordóñez ÁJ. Grupos sanguíneos y enfermedad. Med Clin (Barc) [Internet]. 2005;125(10):382–8. Available from: http://dx.doi.org/10.1157/13079179
2. Anstee DJ. The relationship between blood groups and disease. Blood. 2010;115(23):4635–43. Available from: https://doi.org/10.1182/blood-2010-01-261859
3. Arbeláez- García C. Sistema de grupo sanguineo ABO. Med Lab [Internet]. 2009;15(7):329–47. Available from: Available from: https://www.medigraphic.com/pdfs/medlab/myl-2009/myl097-8c.pdf.
4. Franchini, Massimo and Liumbruno GM. “ABO blood group: old dogma, new perspectives.” Clin Chem Lab Med. 2013;51(8):1545–53. Available from: https://pubmed.ncbi.nlm.nih.gov/23648637/DOI: 10.1515/cclm-2013-0168
5. Zhang H, Mooney CJ, Reilly MP. ABO blood groups and cardiovascular diseases. Int J Vasc Med. 2012;2012. Available from: https://pubmed.ncbi.nlm.nih.gov/23133757/ DOI: 10.1155/2012/641917
6. Edgren G, Hjalgrim H, Rostgaard K, Norda R, Wikman A, Melbye M, et al. Risk of gastric cancer and peptic ulcers in relation to ABO blood type: A cohort study. Am J Epidemiol. 2010;172(11):1280–5. Available from: https://pubmed.ncbi.nlm.nih.gov/20937632/ DOI: 10.1093/aje/kwq299
7. Wolpin BM, Chan AT, Hartge P, Chanock SJ, Kraft P, Hunter DJ, et al. ABO blood group and the risk of pancreatic cancer. J Natl Cancer Inst. 2009;101(6):424–31. Available from:https://pubmed.ncbi.nlm.nih.gov/19276450/ DOI: 10.1093/jnci/djp020
8. JAIME C-F. Frecuencia de los grupos sanguíneos ABO y Rh en la población laboral del valle de Aburrá y del cercano oriente de Antioquia (Colombia). Acta Médica Colomb [Internet]. 2006;31(1):20–30. Available from: https://www.redalyc.org/pdf/1631/163114147009.pdf
9. Del Peón-Hidalgo L, Pacheco-Cano MG, Zavala-Ruiz M, Madueño-López A, García-Gonzáles A. Frecuencias de grupos sanguíneos e incompatibilidades ABO y, RhD, en La Paz, Baja California Sur, México. Salud Publica Mex. 2002;44(5):406–12. Available from:http://www.insp.mx/salud/index.html
10. Pérez Escobar, Rocío, Betancur Ceballos, Carolina, López Mendoza, Andrea, Saavedra Perea, Juana, Ríos Osorio L. Frecuencia de los principales grupos sanguíneos del sistema ABO y el factor Rh en seis municipios del área rural del departamento de Antioquia y el Atrato Medio, Colombia, 2005. Hechos Microbiol. 2010;1(2):27–33. Available from: https://revistas.udea.edu.co/index.php/hm/article/view/9548
11. Fagherazzi G, Gusto G, Clavel-Chapelon F, Balkau B, Bonnet F. ABO and Rhesus blood groups and risk of type 2 diabetes: evidence from the large E3N cohort study. Diabetologia. 2015;58(3):519–22. Available from: https://pubmed.ncbi.nlm.nih.gov/25533388/ DOI: 10.1007/s00125-014-3472-9
12. Huidobro Muñoz A, Torres C. D, Paredes F. Diabetes Gestacional: Asociación con grupo ABO. Rev Med Chil. 2017;145(4):431–5. Available from:http://dx.doi.org/10.4067/S0034-98872017000400002
13. Li X, Xu H, Gao P. ABO Blood Group and Diabetes Mellitus Influence the Risk for Pancreatic Cancer in a Population from China. 2018;9392–8. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320638/doi: 10.12659/MSM.913769
14. Biswas S, Ghoshal PK, Halder B, Mandal N. Distribution of ABO blood group and major cardiovascular risk factors with coronary heart disease. Biomed Res Int. 2013;2013. Available from: https://doi.org/10.1155/2013/782941
15. Vasan SK, Rostgaard K, Majeed A, Ullum H, Titlestad KE, Pedersen OBV, et al. ABO Blood Group and Risk of Thromboembolic and Arterial Disease: A Study of 1.5 Million Blood Donors. Circulation. 2016;133(15):1449–57. Available from:DOI: 10.1161/CIRCULATIONAHA.115.017563
16. Franchini M, Lippi G. The intriguing relationship between the ABO blood group, cardiovascular disease, and cancer. BMC Med. 2015;13(1):1–3. Available from: DOI https://doi.org/10.1186/s12916-014-0250-y
17. Chowdhary S, Sharma V, Chowdhary S. Study of association of ABO blood group with ischemic heart disease. Int J Med Sci Public Heal. 2016;5(3):468. Available from doi: 10.5455/ijmsph.2016.0408201584
18. Li Y, Liu L, Huang Y, Zheng H, Li L. Association of ABO polymorphisms and pancreatic Cancer/ Cardiocerebrovascular disease: A meta-Analysis. BMC Med Genet. 2020;21(1):1–10. Available from: doi: 10.1186/s12881-020-0975-8
19. Tanaka Y, Kumagi T, Terao T, Kuroda T, Yokota T, Yukimoto A, et al. ABO Blood Type and the Long-term Outcomes of Pancreatic Cancer. 2020;761–8. Available from: doi: 10.2169/internalmedicine.3748-19
20. Nakao M, Matsuo K, Ito H, Shitara K, Hosono S, Watanabe M. ABO Genotype and the Risk of Gastric Cancer , Atrophic Gastritis , and Helicobacter pylori Infection. 2011;1665–73. Available from:DOI: 10.1158/1055-9965.EPI-11-0213
21. Chakrani Z, Robinson K, Taye B. Association Between ABO Blood Groups and Helicobacter pylori Infection: A Meta-Analysis. Sci Rep [Internet]. 2018;8(1):1–11. Available from: http://dx.doi.org/10.1038/s41598-018-36006-x
22. Press D. Relation between ABO blood groups and Helicobacter pylori infection in symptomatic patients. 2011;221–6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3190290/ doi: 10.2147/CEG.S23019
23. Lawrence Tim Goodnough, MDa B, Anil K. Panigrahi, MD, PhDa C. Blood Transfusion Therapy. Med Clin North Am. 2017;101(2):431–47. Available from: https://pubmed.ncbi.nlm.nih.gov/28189180/ DOI: 10.1016/j.mcna.2016.09.012
24. Quintero M, M.D. Jimenez M. Anemia de celulas falciformes m. Rev Gastrohnup. 2012;14(2):27–35. Available from: https://revgastrohnup.univalle.edu.co/a12v14n2s1/a12v14n2s1art4.pdf
25. Salomón-Cruz J, Gómez-Valencia L, Morales-Hernández A. Estudio clínico y genético de tres casos de anemia de células falciformes. Salud en Tabasco. 2006;12(2):440–2. Available from: https://www.redalyc.org/pdf/487/48712206.pdf
26. Fong C, Menzel S, Lizarralde MA, Barreto G. Genetic variants associated with fetal hemoglobin levels show the diverse ethnic origin in Colombian patients with sickle cell anemia. Biomedica. 2015;35(3):437–43. Available from: http://dx.doi.org/10.7705/biomedica.v35i3.2573
27. Pelcovits A, Niroula R. Acute Myeloid Leukemia: A Review. R I Med J (2013) [Internet]. 2020;103(3):38–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32236160
28. De Kouchkovsky I, Abdul-Hay M. ‘Acute myeloid leukemia: A comprehensive review and 2016 update.’ Blood Cancer J. 2016;6(7). Available from: https://pubmed.ncbi.nlm.nih.gov/27367478/doi: 10.1038/bcj.2016.50.
Information
Keywords
