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Determination of microdeletion in chromosome Y in infertile men, candidates to assistedreproduction techniques Intracytoplasmatic spermatozoid Injection

Determinación de deleciones en el cromosoma Y en hombres infértiles candidatos a técnicas de reproducción asistida




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Lucena Q, E., Pérez, C. E., & Kent First, M. (2004). Determination of microdeletion in chromosome Y in infertile men, candidates to assistedreproduction techniques Intracytoplasmatic spermatozoid Injection. NOVA, 2(2). https://doi.org/10.22490/24629448.3

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Elkin Lucena Q
    Clara Esteban Pérez
      Marijo Kent First

        Severe spermatic damage in infertile man can be the result of presence of deletion in chromosome Y and in AFZc region (Zoosperm factor Zone C). This study was made in 97 men with infertility and a frequency of 6% to the presence of deletion in the studied population. Of those men positive to deletion in Zone Yq (AZFc) were born three children by using intracytoplasmatic injection (ICSI), whom inherited mutation in chromosome Y, it established the importance to create a sifting program to detect the presence of deletion in this chromosome infertile men population, candidates to Assisted Reproduction Technique treatments (ART) by ICSI.

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        65. DOI: http://dx.doi.org/10.22490/24629448.3
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