Análisis de la población de células T reguladoras Foxp3 en el modelo murino de amibiasis intestinal

Claudia Andrea Cruz; Mauricio Sarrazola; Juan Pedro Laclette

doi:10.22490/24629448.435

Analysis of the population of foxp3 regulatory t cells in the murine model of intestinal amoebiasis

Análisis de la población de células T reguladoras Foxp3 en el modelo murino de amibiasis intestinal

Published 2010-06-30

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Vol. 8 No. 13 (2010)

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Artículo Original

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Cruz, C. A., Sarrazola, M., & Laclette, J. P. (2010). Analysis of the population of foxp3 regulatory t cells in the murine model of intestinal amoebiasis. NOVA, 8(13). https://doi.org/10.22490/24629448.435

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https://doi.org/10.22490/24629448.435

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NOVA by http://www.unicolmayor.edu.co/publicaciones/index.php/nova is distributed under a license creative commons non comertial-atribution-withoutderive 4.0 international.

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Claudia Andrea Cruz

Mauricio Sarrazola

Juan Pedro Laclette

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Amebiasis

Treg cells

Entamoeba histolytica

Splenocytes trophozoites

Amebiasis is a parasitic infection caused by E. histolytica, its incidence is higher in developing countries. Recently we have studied the role of Treg cells in several parasitic diseases, which can have beneficial or harmful. The goal of this project was to investigate the role of Treg cells in an immunosuppressive phenomenon previously observed on mouse model of intestinal amoebiasis. Thus, the behavior of Treg population cells was studied at different periods post-infection. However, the results suggest that Treg cells are not involved in this phenomenon of immunosuppression.

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DOI: http://dx.doi.org/10.22490/24629448.435