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Quantification of free DNA in blood plasma of healthy volunteers in Bogotá population

Cuantificación de ADN libre en plasma sanguíneo de voluntarios sanos en una población bogotana




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Quantification of free DNA in blood plasma of healthy volunteers in Bogotá population. (2009). NOVA, 7(12). https://doi.org/10.22490/24629448.427

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NOVA by http://www.unicolmayor.edu.co/publicaciones/index.php/nova is distributed under a license creative commons non comertial-atribution-withoutderive 4.0 international.

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Hernán David Salazar-Jordan et al.

    The free DNA in blood increases with some pathological conditions and certain physiological state. Several reports in the literature have highlighted that the free DNA in plasma or serum has clinical potential as a possible tool for the prognosis of human cancer. However, so far there are no reference values of healthy individuals with a representative sample size and no values have been reported for specific populations such as Bogota. That is why in this study we quantified the concentration of free DNA in healthy people of the Bogota population and thus established a normal range or reference value, the relationship between levels of free DNA and characteristics such as age and gender was further analyzed. The concentration of free DNA in the Bogota population was 0.72 ng/μL and no significant differences between ages and genders were found.

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    23. DOI: http://dx.doi.org/10.22490/24629448.427
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