Metabolomics and pesticides: systematic literature review using graph theory for analysis of references

Metabolómica y Pesticidas: Revisión sistemática de literatura usando teoría de grafos para el análisis de referencias

Publicado 2017-03-22

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Vol. 14 Núm. 25 (2016)
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Zuluaga, M., Robledo, S., Osorio-Zuluaga, G. A., Yathe, L., Gonzalez, D., & Taborda, G. (2017). Metabolomics and pesticides: systematic literature review using graph theory for analysis of references. REVISTA NOVA , 14(25), 121-138. https://doi.org/10.22490/24629448.1735
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https://doi.org/10.22490/24629448.1735
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NOVA por http://www.unicolmayor.edu.co/publicaciones/index.php/nova se distribuye bajo una Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional.

Así mismo,  los autores mantienen sus derechos de propiedad intelectual sobre los artículos.  

Martha Zuluaga
Universidad de Caldas
    Sebastian Robledo
    Universidad Nacional de Colombia
      German A Osorio-Zuluaga
      Universidad Nacional de Colombia
        Laura Yathe
        Universidad de Caldas
          Diana Gonzalez
          Universidad de Caldas
            Gonzalo Taborda
              Mostrar biografía de los autores

              La revisión sistemática de literatura presentada a continuación tiene como objetivo dar a conocer el rol que han tenido la metabolómica en el estudio de la exposición a plaguicidas. La búsqueda se llevó a cabo en la base de datos Thomson Reuters Web of Science (ISI Web of Knowledge). Posteriormente, se descargaron todos los registros producto de resultado de la búsqueda y cada citación dentro de cada artículo. Estas referencias fueron analizadas mediante la teoría de grafos con el fin de identificar los artículos más relevantes, los artículos clásicos y recientes y los que presentan mayor intermediación en el tema de investigación. La red de citaciones fue construida con inicialmente con 4423 nodos (artículos) y 4978 enlaces (citaciones) a los cuales se les determinó los indicadores de grado de entrada, grado de salida y centralidad en el grafo. Posteriormente, esta red de citaciones fue procesada eliminando los artículos desconectados, reduciendo la red a 415 nodos y 974 enlaces. De esta red ya procesada se extrajeron 80 artículos que presentaron mayores indicadores de grado y centralidad. Finalmente, esta metodología permitió la identificación de diferentes perspectivas de los estudios metabolómicos y metabonómicos en la exposición a plaguicidas que incluyen estudios de modo de acción, mecanismos de acción, monitoreo biológico y toxicológico, metabolómica ambiental, metabolismo, dosis respuesta e identificación de biomarcadores.

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              100. ==========================================
              101. DOI: http://dx.doi.org/10.22490/24629448.1735
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